Oxymetholone Side Effects


Anadrol (Oxymetholone) is an oral anabolic and androgenic derivative from DHT steroid with pretty harsh side effects. This anabolic steroid is often considered one of the most powerful oral steroids on the market. This means that while it can significantly increase muscle mass, size, and strength, it may cause some significant side effects too.

A general rule is – the more powerful a compound is, the more likely it is to cause side effects. Considering that Anadrol (Oxymetholone) is extremely powerful – side effects obviously can be pretty harsh.

  • Nevertheless, Anadrol is still one of the few steroids out there that still has FDA approval. Other steroids to mention are Anavar, Deca Durabolin, and obviously, Testosterone. While this doesn’t mean that Anadrol side effects won’t occur, it indicates that this steroid is safe as long as you’re using it correctly.

Remember that the higher the dosage and the longer the cycle length – the nastier Oxymetholone side effects can be. Moreover, your genetics and environment (lifestyle habits) will greatly dictate how harsh the side effects can be. That’s why it’s very important to make sure that you’re a healthy individual (those with pre-existing health issues may find that Anadrol exacerbates those issues) who has a proper lifestyle (dieting, working out, avoiding bad habits, etc.) and uses Anadrol responsibly.

Additionally, considering that Anadrol side effects are generally worse than the side effects of other steroids that are generally milder, I do not recommend Anadrol to beginners. There are much better and safer options than Anadrol to start with. Its immense power makes it attractive to steroid beginners, but the possible side effects make it a poor choice. It’s a much better option for at least intermediate users or best for steroid professionals.


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Oxymetholone Side Effects List

As said, Anadrol (Oxymetholone) produces some of the best results in terms of strength and mass gains. But it is a harsh steroid. That’s why the list of side effects that you will see here is likely to be worse than with other steroids out there.

Some of them include:

  • Liver toxicity
  • Water retention
  • High blood pressure
  • Gynecomastia
  • Natural testosterone suppression
  • Hair loss
  • Acne
  • Cardiovascular and cholesterol issues

Liver Toxicity

Oxymetholone is among the most liver toxic steroids on the market. It is orally active and is a C17 AA steroid. As with any other oral C17AA steroids, they are straining your liver. According to studies, Oxymetholone seems to be even more liver strenuous than others.

For this reason, I strongly recommend keeping cycles within a 4-6 weeks length limit. I also strongly recommend implementing all the methods required to keep a healthy liver. Such as using liver protection/cleansing supplements and avoiding anything that damages the liver even more such as other hepatotoxic compounds like oral steroids, specific medications, or alcohol.

Testosterone Suppression

All anabolic and androgenic steroids are suppressive to natural testosterone production. Anadrol is not an exception. For this reason, you should implement a Post Cycle Therapy (PCT) plan after each use of Anadrol or any other steroid cycle. Moreover, I strongly recommend adding testosterone to your Anadrol (or other steroids) cycle.

Adding testosterone will make sure that your body gets enough testosterone to function properly and enhances the efficacy of the cycle. The PCT is important for recovering back natural testosterone production. Without PCT, it will leave you with lots of months of suffering from low testosterone. Except for the fact that you may lose all the gains made during the cycle due to low T, it’s also unhealthy. A PCT plan is very important after finishing any steroid cycle. Especially if talking about powerful steroids like Oxymetholone.

Androgenic Side Effects

Again, all anabolic and androgenic steroids can cause androgenic side effects. Some are more dangerous than others in this aspect depending on their androgenic activity. Oxymetholone is moderately androgenic, but some pretty bad androgenic issues are still possible because of its DHT nature.

Additionally, Oxymetholone side effects in regard to androgenic activity highly depend on the genetics of the individual using it. That’s true in regard to any anabolic steroids. For example, people who are prone to hair loss, acne, or aggression are more likely to experience them even with lower dosages. But people without these genetic traits may not experience any of these issues even in higher doses.

Estrogenic Side Effects

Anadrol is immune to aromatization. It doesn’t bind to aromatase enzymes, therefore, it will not increase estrogen levels. Despite that, among Oxymetholone side effects you could notice water retention, bloating, and gynecomastia which are the most common estrogenic side effects. That’s because Anadrol is capable of binding to estrogen receptors, working as estrogen itself. That’s why estrogenic issues can occur despite the fact that estrogen levels will not increase.

Due to this, aromatase inhibitors are ineffective to deal with estrogenic issues. You can only control gynecomastia with the help of Nolvadex (Tamoxifen) because it doesn’t lower estrogen as AIs do, it binds directly to estrogen receptors in breast tissues. But because of all of this, there’s no way you can control water retention and bloating. AIs will not be effective. The only (limited) way to control water retention and bloating is through diet. Mainly by reducing sodium intake.

Cardiovascular Issues

I said that Oxymetholone will negatively impact your liver. But the liver is very important for maintaining healthy cholesterol values. Due to its hepatotoxicity, cholesterol issues are possible, as with any other oral steroid. In fact, oral steroids are even worse than injectables because all steroids will negatively shift your HDL to LDL cholesterol ratio. Mainly due to an increase in hormones. More so will Anadrol.

Moreover, Anadrol will cause water retention that can be pretty bad and there’s no way you can control that. An increase in water retention usually leads to higher blood pressure. The negative impact on cholesterol also leads to an increase in blood pressure. All of this makes it very possible to suffer from hypertension while on an Anadrol cycle. The cardiovascular strain can be pretty bad and in fact, it’s one of the most serious and dangerous issues that you should be watching out for while using this anabolic steroid.



Oxymetholone side effects can be pretty bad, but as long as you use it correctly, you can manage them very well. The side effects are tolerable as long as you use it with caution and as long as you use high quality Oxymetholone.

At Anabolics Steroids, you can get information on how to use it correctly and can Buy the best quality Anadrol. This is the source of anabolic steroids where you can get everything you need for a successful cycle. The steroids themselves are of the best quality for the cheapest prices alongside helpful information about how to run them.


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